Spasmolytic Polypeptide (TFF2) (NM_005423) Human Recombinant Protein
Product Specifications
Background
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]
Synonyms
SML1; SP
Gene ID
7032
UniProt
Q03403
Accession Number mRNA
NM_005423
Chromosomal Location
21q22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein
Molecular Weight
11.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
TFF2
Species
Human
Protein ID
NP_005414
Overview
Recombinant protein of human trefoil factor 2 (TFF2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/7032
Uniprot URL
https://www.uniprot.org/uniprot/Q03403
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005423
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005414
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