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Spasmolytic Polypeptide (TFF2) (NM_005423) Human Recombinant Protein

Product Specifications

Background

Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. The encoded protein inhibits gastric acid secretion. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human trefoil factor 2 (TFF2)

Synonyms

SML1; SP

Gene ID

7032

UniProt

Q03403

Accession Number mRNA

NM_005423

Chromosomal Location

21q22.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Secreted Protein

Molecular Weight

11.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

TFF2

Species

Human

Protein ID

NP_005414

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7032

Uniprot URL

https://www.uniprot.org/uniprot/Q03403

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_005423

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_005414

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