CA7 (NM_001014435) Human Recombinant Protein
Selected Variant
PH38438M5
Size: 20 µg
Product Specifications
Background
Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the brain and contributes to bicarbonate driven GABAergic neuron excitation. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2018]
Overview
Recombinant protein of human carbonic anhydrase VII (CA7), transcript variant 2
Synonyms
CA-VII; CAVII
Gene ID
766
UniProt
P43166
Accession Number mRNA
NM_001014435
Chromosomal Location
16q22.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Nitrogen metabolism
Field of Research
Nitrogen metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
23.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CA7
Species
Human
Protein ID
NP_001014435
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/766
Uniprot URL
https://www.uniprot.org/uniprot/P43166
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001014435
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001014435
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