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CA7 (NM_001014435) Human Recombinant Protein

Selected Variant

PH38438M5

Size: 20 µg

Product Specifications

Background

Carbonic anhydrases are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. The cytosolic protein encoded by this gene is predominantly expressed in the brain and contributes to bicarbonate driven GABAergic neuron excitation. Alternative splicing in the coding region results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2018]

Overview

Recombinant protein of human carbonic anhydrase VII (CA7), transcript variant 2

Synonyms

CA-VII; CAVII

Gene ID

766

UniProt

P43166

Accession Number mRNA

NM_001014435

Chromosomal Location

16q22.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Nitrogen metabolism

Field of Research

Nitrogen metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

23.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CA7

Species

Human

Protein ID

NP_001014435

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/766

Uniprot URL

https://www.uniprot.org/uniprot/P43166

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_001014435

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_001014435

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