GPNMB (NM_001005340) Human Recombinant Protein
Selected Variant
PH38415M5
Size: 20 µg
Product Specifications
Background
The protein encoded by this gene is a type I transmembrane glycoprotein which shows homology to the pMEL17 precursor, a melanocyte-specific protein. GPNMB shows expression in the lowly metastatic human melanoma cell lines and xenografts but does not show expression in the highly metastatic cell lines. GPNMB may be involved in growth delay and reduction of metastatic potential. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human glycoprotein (transmembrane) nmb (GPNMB), transcript variant 1
Synonyms
HGFIN; NMB; PLCA3
Gene ID
10457
UniProt
Q14956
Accession Number mRNA
NM_001005340
Chromosomal Location
7p15.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
26751287
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transmembrane
Molecular Weight
61.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GPNMB
Species
Human
Protein ID
NP_001005340
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10457
Uniprot URL
https://www.uniprot.org/uniprot/Q14956
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001005340
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001005340
Price
Sign In for Pricing
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
PA1469-FITC 100 µg/Vial
Anti-Interleukin-13 IL13 Antibody Picoband®, FITC Conjugate
Sign In for Pricing
View Details 
BNC401498-100 1x 100 µL
CD20 / MS4A1 (B-Cell Marker), CF640R conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC042981-100 1x 100 µL
Tenascin C (Stromal Marker For Epithelial Malignancy) (TNC/2981R), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC041976-500 1x 500 µL
CD27 (Tumor Necrosis Factor Receptor Superfamily 7) (rLPFS2/1611), CF405S conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC473128-100 1x 100 µL
Cytochrome C (Mitochondrial Marker) (CYCS/3128R), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details 
BNC472954-100 1x 100 µL
C1QA / Complement C1q A-Chain (C1QA/2954), CF647 conjugate, 0.1mg/mL
Sign In for Pricing
View Details