DOK2 (NM_003974) Human Recombinant Protein
Selected Variant
PH38411M5
Size: 20 µg
Product Specifications
Background
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human docking protein 2, 56kDa (DOK2)
Synonyms
P56DOK; p56dok-2
Gene ID
9046
UniProt
O60496
Accession Number mRNA
NM_003974
Chromosomal Location
8p21.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
45.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DOK2
Species
Human
Protein ID
NP_003965
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9046
Uniprot URL
https://www.uniprot.org/uniprot/O60496
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003974
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003965
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