What is the catalog number for XIAP (NM_001167) Human Recombinant Protein?

The catalog number for XIAP (NM_001167) Human Recombinant Protein is PH38409M5.

What sizes are available for XIAP (NM_001167) Human Recombinant Protein?

XIAP (NM_001167) Human Recombinant Protein is available in the following size(s): 20 µg.

Is XIAP (NM_001167) Human Recombinant Protein in stock?

XIAP (NM_001167) Human Recombinant Protein is currently made to order / not held in immediate stock. Contact us for lead time.

XIAP (NM_001167) Human Recombinant Protein

Product Specifications

Background

This gene encodes a protein that belongs to a family of apoptotic suppressor proteins. Members of this family share a conserved motif termed, baculovirus IAP repeat, which is necessary for their anti-apoptotic function. This protein functions through binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2 and inhibits apoptosis induced by menadione, a potent inducer of free radicals, and interleukin 1-beta converting enzyme. This protein also inhibits at least two members of the caspase family of cell-death proteases, caspase-3 and caspase-7. Mutations in this gene are the cause of X-linked lymphoproliferative syndrome. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 2 and 11.[provided by RefSeq, Feb 2011]

Overview

Recombinant protein of human X-linked inhibitor of apoptosis (XIAP)

Synonyms

API3; BIRC4; hIAP-3; hIAP3; IAP-3; ILP1; MIHA; XLP2

Gene ID

331

UniProt

P98170

Accession Number mRNA

NM_001167

Chromosomal Location

Xq25

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Apoptosis, Focal adhesion, NOD-like receptor signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis

Field of Research

Apoptosis, Focal adhesion, NOD-like receptor signaling pathway, Pathways in cancer, Small cell lung cancer, Ubiquitin mediated proteolysis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

56.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.