ANKRD13B (NM_152345) Human Recombinant Protein

Product Specifications

Background

Ubiquitin-binding protein that specifically recognizes and binds 'Lys-63'-linked ubiquitin. Does not bind 'Lys-48'-linked ubiquitin. Positively regulates the internalization of ligand-activated EGFR by binding to the Ub moiety of ubiquitinated EGFR at the cell membrane.[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human ankyrin repeat domain 13B (ANKRD13B)

Synonyms

FLJ20418; FLJ25555

Gene ID

124930

UniProt

Q86YJ7, A0A024QZ29, B3KS27

Accession Number mRNA

NM_152345

Chromosomal Location

17q11.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

70 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.