TXNDC3 (NME8) (NM_016616) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein with an N-terminal thioredoxin domain and three C-terminal nucleoside diphosphate kinase (NDK) domains, but the NDK domains are thought to be catalytically inactive. The sea urchin ortholog of this gene encodes a component of sperm outer dynein arms, and the protein is implicated in ciliary function. Mutations in this gene are implicated in primary ciliary dyskinesia type 6.[provided by RefSeq, Nov 2009]
Overview
Recombinant protein of human thioredoxin domain containing 3 (spermatozoa) (TXNDC3)
Synonyms
CILD6; DNAI8; HEL-S-99; NM23-H8; sptrx-2; SPTRX2; TXNDC3
Gene ID
51314
UniProt
Q8N427
Accession Number mRNA
NM_016616
Chromosomal Location
7p14.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
67.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NME8
Species
Human
Protein ID
NP_057700
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/51314
Uniprot URL
https://www.uniprot.org/uniprot/Q8N427
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_016616
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_057700
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