P4HA2 (NM_001017973) Human Recombinant Protein
Product Specifications
Background
This gene encodes a component of prolyl 4-hydroxylase, a key enzyme in collagen synthesis composed of two identical alpha subunits and two beta subunits. The encoded protein is one of several different types of alpha subunits and provides the major part of the catalytic site of the active enzyme. In collagen and related proteins, prolyl 4-hydroxylase catalyzes the formation of 4-hydroxyproline that is essential to the proper three-dimensional folding of newly synthesized procollagen chains. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
Synonyms
MYP25
Gene ID
8974
UniProt
O15460
Accession Number mRNA
NM_001017973
Chromosomal Location
5q31.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Arginine and proline metabolism, Metabolic pathways
Field of Research
Arginine and proline metabolism, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
58.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
P4HA2
Species
Human
Protein ID
NP_001017973
Overview
Recombinant protein of human prolyl 4-hydroxylase, alpha polypeptide II (P4HA2), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8974
Uniprot URL
https://www.uniprot.org/uniprot/O15460
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001017973
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001017973
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