EXOC8 (NM_175876) Human Recombinant Protein
Product Specifications
Background
This gene encodes a component of the exocyst complex, an evolutionarily conserved multi-protein complex that plays a critical role in vesicular trafficking and the secretory pathway by targeting post-Golgi vesicles to the plasma membrane. This protein is a target of activated Ral subfamily of GTPases and thereby regulates exocytosis by tethering vesicles to the plasma membrane. Mutations in this gene may be related to Joubert syndrome. [provided by RefSeq, Sep 2016]
Overview
Recombinant protein of human exocyst complex component 8 (EXOC8)
Synonyms
EXO84; Exo84p; NEDMISB; SEC84
Gene ID
149371
UniProt
Q8IYI6
Accession Number mRNA
NM_175876
Chromosomal Location
1q42.2
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
81.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EXOC8
Species
Human
Protein ID
NP_787072
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/149371
Uniprot URL
https://www.uniprot.org/uniprot/Q8IYI6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_175876
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_787072
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