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CROT (NM_021151) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the carnitine/choline acetyltransferase family. The encoded protein converts 4,8-dimethylnonanoyl-CoA to its corresponding carnitine ester. This transesterification occurs in the peroxisome and is necessary for transport of medium- and long- chain acyl-CoA molecules out of the peroxisome to the cytosol and mitochondria. The protein thus plays a role in lipid metabolism and fatty acid beta-oxidation. Alternatively spliced transcript variants have been described.[provided by RefSeq, Jan 2009]

Overview

Recombinant protein of human carnitine O-octanoyltransferase (CROT), transcript variant 2

Synonyms

COT

Gene ID

54677

UniProt

Q9UKG9

Accession Number mRNA

NM_021151

Chromosomal Location

7q21.12

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

70 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

CROT

Species

Human

Protein ID

NP_066974

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/54677

Uniprot URL

https://www.uniprot.org/uniprot/Q9UKG9

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_021151

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_066974

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