PDSS2 (NM_020381) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is an enzyme that synthesizes the prenyl side-chain of coenzyme Q, or ubiquinone, one of the key elements in the respiratory chain. The gene product catalyzes the formation of all trans-polyprenyl pyrophosphates from isopentyl diphosphate in the assembly of polyisoprenoid side chains, the first step in coenzyme Q biosynthesis. Defects in this gene are a cause of coenzyme Q10 deficiency.[provided by RefSeq, Oct 2009]

Overview

Recombinant protein of human prenyl (decaprenyl) diphosphate synthase, subunit 2 (PDSS2)

Synonyms

BA59I9.3; C6orf210; COQ1B; COQ10D3; DLP1; hDLP1

Gene ID

57107

UniProt

Q86YH6

Accession Number mRNA

NM_020381

Chromosomal Location

6q21

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Terpenoid backbone biosynthesis

Field of Research

Terpenoid backbone biosynthesis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

43.9 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.