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Pentraxin 3 (PTX3) (NM_002852) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions. [provided by RefSeq, Jun 2016]

Overview

Recombinant protein of human pentraxin-related gene, rapidly induced by IL-1 beta (PTX3)

Synonyms

TNFAIP5; TSG-14

Gene ID

5806

UniProt

P26022

Accession Number mRNA

NM_002852

Chromosomal Location

3q25.32

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Secreted Protein

Molecular Weight

41.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

PTX3

Species

Human

Protein ID

NP_002843

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/5806

Uniprot URL

https://www.uniprot.org/uniprot/P26022

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002852

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002843

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