NSMAF (NM_003580) Human Recombinant Protein
Product Specifications
Background
This gene encodes a WD-repeat protein that binds the cytoplasmic sphingomyelinase activation domain of the 55kD tumor necrosis factor receptor. This protein is required for TNF-mediated activation of neutral sphingomyelinase and may play a role in regulating TNF-induced cellular responses such as inflammation. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2009]
Synonyms
FAN; GRAMD5
Gene ID
8439
UniProt
Q92636
Accession Number mRNA
NM_003580
Chromosomal Location
8q12.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
104.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
NSMAF
Species
Human
Protein ID
NP_003571
Overview
Recombinant protein of human neutral sphingomyelinase (N-SMase) activation associated factor (NSMAF), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8439
Uniprot URL
https://www.uniprot.org/uniprot/Q92636
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003580
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003571
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