IGJ (JCHAIN) (NM_144646) Human Recombinant Protein
Product Specifications
Background
Serves to link two monomer units of either IgM or IgA. In the case of IgM, the J chain-joined dimer is a nucleating unit for the IgM pentamer, and in the case of IgA it induces larger polymers. It also help to bind these immunoglobulins to secretory component.[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human immunoglobulin J polypeptide, linker protein for immunoglobulin alpha and mu polypeptides (IGJ)
Synonyms
IGCJ; IGJ; JCH
Gene ID
3512
UniProt
P01591
Accession Number mRNA
NM_144646
Chromosomal Location
4q13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
17.9 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
JCHAIN
Species
Human
Protein ID
NP_653247
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3512
Uniprot URL
https://www.uniprot.org/uniprot/P01591
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_144646
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_653247
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