RIPX (RUFY3) (NM_014961) Human Recombinant Protein
Product Specifications
Background
This gene encodes a RPIP8, UNC-14, and NESCA domain-containing protein that is required for maintenance of neuronal polarity. In addition, it has been implicated in mediation of gastric cancer cell migration and invasion via interaction with P21-activated kinase-1, which promotes its expression. The encoded protein localizes to F-actin-enriched invadopodia to induce formation of protrusions, thereby facilitating cell migration. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Synonyms
RIPX; SINGAR1; ZFYVE30
Gene ID
22902
UniProt
Q7L099, B4DKC2, B4DG59
Accession Number mRNA
NM_014961
Chromosomal Location
4q13.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
52.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RUFY3
Species
Human
Protein ID
NP_055776
Overview
Recombinant protein of human RUN and FYVE domain containing 3 (RUFY3), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/22902
Uniprot URL
https://www.uniprot.org/uniprot/Q7L099
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_014961
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055776
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