P75 NGF Receptor (NGFR) (NM_002507) Human Recombinant Protein

Product Specifications

Background

Nerve growth factor receptor contains an extracellular domain containing four 40-amino acid repeats with 6 cysteine residues at conserved positions followed by a serine/threonine-rich region, a single transmembrane domain, and a 155-amino acid cytoplasmic domain. The cysteine-rich region contains the nerve growth factor binding domain. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human nerve growth factor receptor (TNFR superfamily, member 16) (NGFR)

Synonyms

CD271; Gp80-LNGFR; p75 (NTR) ; p75NTR; TNFRSF16

Gene ID

4804

UniProt

P08138

Accession Number mRNA

NM_002507

Chromosomal Location

17q21.33

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Cytokine-cytokine receptor interaction, Neurotrophin signaling pathway

Field of Research

Cytokine-cytokine receptor interaction, Neurotrophin signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transmembrane

Molecular Weight

42.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.