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ACSL3 (NM_004457) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme is highly expressed in brain, and preferentially utilizes myristate, arachidonate, and eicosapentaenoate as substrates. The amino acid sequence of this isozyme is 92% identical to that of rat homolog. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human acyl-CoA synthetase long-chain family member 3 (ACSL3), transcript variant 1

Synonyms

ACS3; FACL3; LACS 3; LACS3; PRO2194

Gene ID

2181

UniProt

O95573, A0A024R487

Accession Number mRNA

NM_004457

Chromosomal Location

2q36.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Adipocytokine signaling pathway, Fatty acid metabolism, Metabolic pathways, PPAR signaling pathway

Field of Research

Adipocytokine signaling pathway, Fatty acid metabolism, Metabolic pathways, PPAR signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transmembrane

Molecular Weight

80.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ACSL3

Species

Human

Protein ID

NP_004448

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2181

Uniprot URL

https://www.uniprot.org/uniprot/O95573

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004457

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004448

Frequently Asked Questions

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