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RABEP1 (NM_004703) Human Recombinant Protein

Product Specifications

Background

Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane (PubMed:22841712) . Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium (By similarity) .[UniProtKB/Swiss-Prot Function]

Overview

Recombinant protein of human rabaptin, RAB GTPase binding effector protein 1 (RABEP1), transcript variant 1

Synonyms

RAB5EP; RABPT5

Gene ID

9135

UniProt

Q15276

Accession Number mRNA

NM_004703

Chromosomal Location

17p13.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Endocytosis

Field of Research

Endocytosis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

99.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

RABEP1

Species

Human

Protein ID

NP_004694

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9135

Uniprot URL

https://www.uniprot.org/uniprot/Q15276

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004703

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004694

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