RABEP1 (NM_004703) Human Recombinant Protein
Product Specifications
Background
Rab effector protein acting as linker between gamma-adaptin, RAB4A and RAB5A. Involved in endocytic membrane fusion and membrane trafficking of recycling endosomes. Involved in KCNH1 channels trafficking to and from the cell membrane (PubMed:22841712) . Stimulates RABGEF1 mediated nucleotide exchange on RAB5A. Mediates the traffic of PKD1:PKD2 complex from the endoplasmic reticulum through the Golgi to the cilium (By similarity) .[UniProtKB/Swiss-Prot Function]
Overview
Recombinant protein of human rabaptin, RAB GTPase binding effector protein 1 (RABEP1), transcript variant 1
Synonyms
RAB5EP; RABPT5
Gene ID
9135
UniProt
Q15276
Accession Number mRNA
NM_004703
Chromosomal Location
17p13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Endocytosis
Field of Research
Endocytosis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
99.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
RABEP1
Species
Human
Protein ID
NP_004694
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/9135
Uniprot URL
https://www.uniprot.org/uniprot/Q15276
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004703
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004694
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