DMRT1 (NM_021951) Human Recombinant Protein
Product Specifications
Background
This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain) . The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human doublesex and mab-3 related transcription factor 1 (DMRT1)
Synonyms
CT154; DMT1
Gene ID
1761
UniProt
Q9Y5R6
Accession Number mRNA
NM_021951
Chromosomal Location
9p24.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Transcription Factors
Molecular Weight
39.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DMRT1
Species
Human
Protein ID
NP_068770
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1761
Uniprot URL
https://www.uniprot.org/uniprot/Q9Y5R6
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_021951
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_068770
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