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DMRT1 (NM_021951) Human Recombinant Protein

Product Specifications

Background

This gene is found in a cluster with two other members of the gene family, having in common a zinc finger-like DNA-binding motif (DM domain) . The DM domain is an ancient, conserved component of the vertebrate sex-determining pathway that is also a key regulator of male development in flies and nematodes. This gene exhibits a gonad-specific and sexually dimorphic expression pattern. Defective testicular development and XY feminization occur when this gene is hemizygous. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human doublesex and mab-3 related transcription factor 1 (DMRT1)

Synonyms

CT154; DMT1

Gene ID

1761

UniProt

Q9Y5R6

Accession Number mRNA

NM_021951

Chromosomal Location

9p24.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transcription Factors

Molecular Weight

39.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

DMRT1

Species

Human

Protein ID

NP_068770

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/1761

Uniprot URL

https://www.uniprot.org/uniprot/Q9Y5R6

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_021951

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_068770

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