PKC delta (PRKCD) (NM_212539) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a member of the protein kinase C family of serine- and threonine-specific protein kinases. The encoded protein is activated by diacylglycerol and is both a tumor suppressor and a positive regulator of cell cycle progression. Also, this protein can positively or negatively regulate apoptosis. Defects in this gene are a cause of autoimmune lymphoproliferative syndrome. [provided by RefSeq, Aug 2017]
Synonyms
ALPS3; CVID9; MAY1; nPKC-delta; PKCD
Gene ID
5580
UniProt
Q05655, A0A024R328
Accession Number mRNA
NM_212539
Chromosomal Location
3p21.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Chemokine signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, GnRH signaling pathway, Neurotrophin signaling pathway, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction
Field of Research
Chemokine signaling pathway, Fc epsilon RI signaling pathway, Fc gamma R-mediated phagocytosis, GnRH signaling pathway, Neurotrophin signaling pathway, Tight junction, Type II diabetes mellitus, Vascular smooth muscle contraction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Protein Kinase
Molecular Weight
77.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PRKCD
Species
Human
Protein ID
NP_997704
Overview
Recombinant protein of human protein kinase C, delta (PRKCD), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/5580
Uniprot URL
https://www.uniprot.org/uniprot/Q05655
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_212539
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_997704
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