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MMP19 (NM_002429) Human Recombinant Protein

Selected Variant

PH38170M5

Size: 20 µg

Product Specifications

Background

This gene encodes a member of a family of proteins that are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. The encoded protein is secreted as an inactive proprotein, which is activated upon cleavage by extracellular proteases. Alternative splicing results in multiple transcript variants for this gene. [provided by RefSeq, Jan 2013]

Overview

Recombinant protein of human matrix metallopeptidase 19 (MMP19), transcript variant 1

Synonyms

CODA; MMP18; RASI-1

Gene ID

4327

UniProt

Q99542

Accession Number mRNA

NM_002429

Chromosomal Location

12q13.2

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Protease, Secreted Protein

Molecular Weight

55.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MMP19

Species

Human

Protein ID

NP_002420

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/4327

Uniprot URL

https://www.uniprot.org/uniprot/Q99542

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002429

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002420

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