ACOX2 (NM_003500) Human Recombinant Protein
Product Specifications
Background
The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe cognitive disability, and death in children. [provided by RefSeq, Mar 2009]
Synonyms
BCOX; BRCACOX; BRCOX; CBAS6; THCCox
Gene ID
8309
UniProt
Q99424
Accession Number mRNA
NM_003500
Chromosomal Location
3p14.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Metabolic pathways, PPAR signaling pathway, Primary bile acid biosynthesis
Field of Research
Metabolic pathways, PPAR signaling pathway, Primary bile acid biosynthesis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
76.6 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ACOX2
Species
Human
Protein ID
NP_003491
Overview
Recombinant protein of human acyl-Coenzyme A oxidase 2, branched chain (ACOX2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8309
Uniprot URL
https://www.uniprot.org/uniprot/Q99424
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_003500
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_003491
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