ACOX2 (NM_003500) Human Recombinant Protein

Product Specifications

Background

The product of this gene belongs to the acyl-CoA oxidase family. It encodes the branched-chain acyl-CoA oxidase which is involved in the degradation of long branched fatty acids and bile acid intermediates in peroxisomes. Deficiency of this enzyme results in the accumulation of branched fatty acids and bile acid intermediates, and may lead to Zellweger syndrome, severe cognitive disability, and death in children. [provided by RefSeq, Mar 2009]

Overview

Recombinant protein of human acyl-Coenzyme A oxidase 2, branched chain (ACOX2)

Synonyms

BCOX; BRCACOX; BRCOX; CBAS6; THCCox

Gene ID

8309

UniProt

Q99424

Accession Number mRNA

NM_003500

Chromosomal Location

3p14.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Metabolic pathways, PPAR signaling pathway, Primary bile acid biosynthesis

Field of Research

Metabolic pathways, PPAR signaling pathway, Primary bile acid biosynthesis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

76.6 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.