GGA1 (NM_001001560) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the Golgi-localized, gamma adaptin ear-containing, ARF-binding (GGA) protein family. Members of this family are ubiquitous coat proteins that regulate the trafficking of proteins between the trans-Golgi network and the lysosome. These proteins share an amino-terminal VHS domain which mediates sorting of the mannose 6-phosphate receptors at the trans-Golgi network. They also contain a carboxy-terminal region with homology to the ear domain of gamma-adaptins. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
ADP-ribosylation factor binding protein 1; gamma-adaptin related protein 1; golgi associated, gamma adaptin ear containing, ARF binding protein 1; OTTHUMP00000028975; OTTHUMP00000042200
Gene ID
26088
UniProt
Q9UJY5
Accession Number mRNA
NM_001001560
Chromosomal Location
22q13.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Lysosome
Field of Research
Lysosome
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
61.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
GGA1
Species
Human
Protein ID
NP_001001560
Overview
Recombinant protein of human golgi associated, gamma adaptin ear containing, ARF binding protein 1 (GGA1), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/26088
Uniprot URL
https://www.uniprot.org/uniprot/Q9UJY5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001001560
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001001560
Curated Selection
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