DGCR6 (NM_005675) Human Recombinant Protein
Product Specifications
Background
DiGeorge syndrome, and more widely, the CATCH 22 syndrome, are associated with microdeletions in chromosomal region 22q11.2. The product of this gene shares homology with the Drosophila melanogaster gonadal protein, which participates in gonadal and germ cell development, and with the gamma-1 subunit of human laminin. This gene is a candidate for involvement in DiGeorge syndrome pathology and in schizophrenia. [provided by RefSeq, Nov 2008]
Synonyms
DiGeorge syndrome critical region gene 6; DiGeorge syndrome critical region protein 6
Gene ID
8214
UniProt
Q14129, X5D7D2
Accession Number mRNA
NM_005675
Chromosomal Location
22q11
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, ES Cell Differentiation/IPS
Molecular Weight
24.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DGCR6
Species
Human
Protein ID
NP_005666
Overview
Purified recombinant protein of Homo sapiens DiGeorge syndrome critical region gene 6 (DGCR6)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/8214
Uniprot URL
https://www.uniprot.org/uniprot/Q14129
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005675
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005666
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