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UGP2 (NM_006759) Human Recombinant Protein

Selected Variant

PH38116M5

Size: 20 µg

Product Specifications

Background

The enzyme encoded by this gene is an important intermediary in mammalian carbohydrate interconversions. It transfers a glucose moiety from glucose-1-phosphate to MgUTP and forms UDP-glucose and MgPPi. In liver and muscle tissue, UDP-glucose is a direct precursor of glycogen; in lactating mammary gland it is converted to UDP-galactose which is then converted to lactose. The eukaryotic enzyme has no significant sequence similarity to the prokaryotic enzyme. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human UDP-glucose pyrophosphorylase 2 (UGP2), transcript variant 1

Synonyms

DEE83; EIEE83; pHC379; SVUGP2; UDPG; UDPGP; UDPGP2; UGP1; UGPP1; UGPP2

Gene ID

7360

UniProt

Q16851

Accession Number mRNA

NM_006759

Chromosomal Location

2p15

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Metabolic pathways, Pentose and glucuronate interconversions, Starch and sucrose metabolism

Field of Research

Amino sugar and nucleotide sugar metabolism, Galactose metabolism, Metabolic pathways, Pentose and glucuronate interconversions, Starch and sucrose metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

56.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

UGP2

Species

Human

Protein ID

NP_006750

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7360

Uniprot URL

https://www.uniprot.org/uniprot/Q16851

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_006759

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_006750

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