DHX8 (NM_004941) Human Recombinant Protein
Product Specifications
Background
This gene is a member of the DEAH box polypeptide family. The encoded protein contains the DEAH (Asp-Glu-Ala-His) motif which is characteristic of all DEAH box proteins, and is thought to function as an ATP-dependent RNA helicase that regulates the release of spliced mRNAs from spliceosomes prior to their export from the nucleus. This protein may be required for the replication of human immunodeficiency virus type 1 (HIV-1) . Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2014]
Overview
Recombinant protein of human DEAH (Asp-Glu-Ala-His) box polypeptide 8 (DHX8)
Synonyms
DDX8; Dhr2; HRH1; PRP22; PRPF22
Gene ID
1659
UniProt
Q14562, Q05CV4, Q86YB2
Accession Number mRNA
NM_004941
Chromosomal Location
17q21.31
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Spliceosome
Field of Research
Spliceosome
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
139.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DHX8
Species
Human
Protein ID
NP_004932
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1659
Uniprot URL
https://www.uniprot.org/uniprot/Q14562
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004941
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004932
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