SEC63 (NM_007214) Human Recombinant Protein
Product Specifications
Background
The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]
Synonyms
DNAJC23; ERdj2; PCLD2; PRO2507; SEC63L
Gene ID
11231
UniProt
Q9UGP8, A0A0S2Z5M1
Accession Number mRNA
NM_007214
Chromosomal Location
6q21
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
87.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SEC63
Species
Human
Protein ID
NP_009145
Overview
Recombinant protein of human SEC63 homolog (S. cerevisiae) (SEC63)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/11231
Uniprot URL
https://www.uniprot.org/uniprot/Q9UGP8
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007214
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_009145
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