FBXO4 (NM_012176) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]
Synonyms
FBX4
Gene ID
26272
UniProt
Q9UKT5, B3KNA0
Accession Number mRNA
NM_012176
Chromosomal Location
5p13.1
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Ubiquitin mediated proteolysis
Field of Research
Ubiquitin mediated proteolysis
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
44 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FBXO4
Species
Human
Protein ID
NP_036308
Overview
Recombinant protein of human F-box protein 4 (FBXO4), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/26272
Uniprot URL
https://www.uniprot.org/uniprot/Q9UKT5
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_012176
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_036308
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