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FBXO4 (NM_012176) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2014]

Overview

Recombinant protein of human F-box protein 4 (FBXO4), transcript variant 1

Synonyms

FBX4

Gene ID

26272

UniProt

Q9UKT5, B3KNA0

Accession Number mRNA

NM_012176

Chromosomal Location

5p13.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Ubiquitin mediated proteolysis

Field of Research

Ubiquitin mediated proteolysis

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome

Molecular Weight

44 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FBXO4

Species

Human

Protein ID

NP_036308

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/26272

Uniprot URL

https://www.uniprot.org/uniprot/Q9UKT5

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_012176

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_036308

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