PARVB (NM_013327) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the parvin family of actin-binding proteins, which play a role in cytoskeleton organization and cell adhesion. These proteins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. This family member binds to alphaPIX and alpha-actinin, and it can inhibit the activity of integrin-linked kinase. This protein also functions in tumor suppression. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2011]
Overview
Recombinant protein of human parvin, beta (PARVB), transcript variant 2
Synonyms
CGI-56
Gene ID
29780
UniProt
Q9HBI1
Accession Number mRNA
NM_013327
Chromosomal Location
22q13.31
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Focal adhesion
Field of Research
Focal adhesion
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
41.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PARVB
Species
Human
Protein ID
NP_037459
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/29780
Uniprot URL
https://www.uniprot.org/uniprot/Q9HBI1
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_013327
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_037459
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