CASC3 (NM_007359) Human Recombinant Protein
Product Specifications
Background
The product of this gene is a core component of the exon junction complex (EJC), a protein complex that is deposited on spliced mRNAs at exon-exon junctions and functions in nonsense-mediated mRNA decay (NMD) . The encoded protein binds RNA and interacts with two other EJC core components. It is predominantly located in the cytoplasm, but shuttles into the nucleus where it localizes to nuclear speckles. [provided by RefSeq, Jul 2008]
Synonyms
BTZ; MLN51
Gene ID
22794
UniProt
O15234
Accession Number mRNA
NM_007359
Chromosomal Location
17q21.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
76.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CASC3
Species
Human
Protein ID
NP_031385
Overview
Recombinant protein of human cancer susceptibility candidate 3 (CASC3)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/22794
Uniprot URL
https://www.uniprot.org/uniprot/O15234
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_007359
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_031385
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