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MAPKAP Kinase 2 (MAPKAPK2) (NM_032960) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2), transcript variant 2

Synonyms

MAPKAP-K2; MK-2; MK2

Gene ID

9261

UniProt

P49137

Accession Number mRNA

NM_032960

Chromosomal Location

1q32.1

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

MAPK signaling pathway, Neurotrophin signaling pathway, VEGF signaling pathway

Field of Research

MAPK signaling pathway, Neurotrophin signaling pathway, VEGF signaling pathway

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Protein Kinase

Molecular Weight

45.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

MAPKAPK2

Species

Human

Protein ID

NP_116584

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/9261

Uniprot URL

https://www.uniprot.org/uniprot/P49137

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_032960

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_116584

Frequently Asked Questions

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