FTCD (NM_006657) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Dec 2009]
Overview
Recombinant protein of human formiminotransferase cyclodeaminase (FTCD), transcript variant B
Synonyms
LCHC1
Gene ID
10841
UniProt
O95954
Accession Number mRNA
NM_006657
Chromosomal Location
21q22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Histidine metabolism, Metabolic pathways, One carbon pool by folate
Field of Research
Histidine metabolism, Metabolic pathways, One carbon pool by folate
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
58.7 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FTCD
Species
Human
Protein ID
NP_006648
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/10841
Uniprot URL
https://www.uniprot.org/uniprot/O95954
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_006657
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_006648
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