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FTCD (NM_006657) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a bifunctional enzyme that channels 1-carbon units from formiminoglutamate, a metabolite of the histidine degradation pathway, to the folate pool. Mutations in this gene are associated with glutamate formiminotransferase deficiency. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Dec 2009]

Overview

Recombinant protein of human formiminotransferase cyclodeaminase (FTCD), transcript variant B

Synonyms

LCHC1

Gene ID

10841

UniProt

O95954

Accession Number mRNA

NM_006657

Chromosomal Location

21q22.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Histidine metabolism, Metabolic pathways, One carbon pool by folate

Field of Research

Histidine metabolism, Metabolic pathways, One carbon pool by folate

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

58.7 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FTCD

Species

Human

Protein ID

NP_006648

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/10841

Uniprot URL

https://www.uniprot.org/uniprot/O95954

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_006657

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_006648

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