CTBP1 (NM_001012614) Human Recombinant Protein
Product Specifications
Background
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Overview
Recombinant protein of human C-terminal binding protein 1 (CTBP1), transcript variant 2
Synonyms
BARS; HADDTS
Gene ID
1487
UniProt
Q13363
Accession Number mRNA
NM_001012614
Chromosomal Location
4p16.3
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Chronic myeloid leukemia, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway
Field of Research
Chronic myeloid leukemia, Notch signaling pathway, Pathways in cancer, Wnt signaling pathway
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
46.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
CTBP1
Species
Human
Protein ID
NP_001012632
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1487
Uniprot URL
https://www.uniprot.org/uniprot/Q13363
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_001012614
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_001012632
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