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TRP1 (TYRP1) (NM_000550) Human Recombinant Protein

Product Specifications

Background

This gene encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. [provided by RefSeq, Mar 2009]

Synonyms

B-PROTEIN; CAS2; CATB; GP75; OCA3; TRP; TRP1; TYRP

Gene ID

7306

UniProt

P17643

Accession Number mRNA

NM_000550

Chromosomal Location

9p23

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Melanogenesis, Metabolic pathways, Tyrosine metabolism

Field of Research

Melanogenesis, Metabolic pathways, Tyrosine metabolism

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Transmembrane

Molecular Weight

58 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

TYRP1

Species

Human

Protein ID

NP_000541

Overview

Recombinant protein of human tyrosinase-related protein 1 (TYRP1)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/7306

Uniprot URL

https://www.uniprot.org/uniprot/P17643

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_000550

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_000541

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