CD31 (PECAM1) (NM_000442) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. [provided by RefSeq, May 2010]

Overview

Recombinant protein of human platelet/endothelial cell adhesion molecule (PECAM1)

Synonyms

CD31; CD31/EndoCAM; endoCAM; GPIIA ; PECA1; PECAM-1

Gene ID

5175

UniProt

P16284

Accession Number mRNA

NM_000442

Chromosomal Location

17q23.3

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Cell adhesion molecules (CAMs), Leukocyte transendothelial migration

Field of Research

Cell adhesion molecules (CAMs), Leukocyte transendothelial migration

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, ES Cell Differentiation/IPS, Transmembrane

Molecular Weight

82.4 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.