EIF4EBP2 (NM_004096) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the eukaryotic translation initiation factor 4E binding protein family. The gene products of this family bind eIF4E and inhibit translation initiation. However, insulin and other growth factors can release this inhibition via a phosphorylation-dependent disruption of their binding to eIF4E. Regulation of protein production through these gene products have been implicated in cell proliferation, cell differentiation and viral infection. [provided by RefSeq, Oct 2008]
Synonyms
4EBP2; PHASII
Gene ID
1979
UniProt
Q13542, A0A024QZM3
Accession Number mRNA
NM_004096
Chromosomal Location
10q22.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
12.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EIF4EBP2
Species
Human
Protein ID
NP_004087
Overview
Recombinant protein of human eukaryotic translation initiation factor 4E binding protein 2 (EIF4EBP2)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/1979
Uniprot URL
https://www.uniprot.org/uniprot/Q13542
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004096
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004087
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