MEF2D (NM_005920) Human Recombinant Protein
Product Specifications
Background
This gene is a member of the myocyte-specific enhancer factor 2 (MEF2) family of transcription factors. Members of this family are involved in control of muscle and neuronal cell differentiation and development, and are regulated by class II histone deacetylases. Fusions of the encoded protein with Deleted in Azoospermia-Associated Protein 1 (DAZAP1) due to a translocation have been found in an acute lymphoblastic leukemia cell line, suggesting a role in leukemogenesis. The encoded protein may also be involved in Parkinson disease and myotonic dystrophy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2012]
Synonyms
DKFZp686I1536
Gene ID
4209
UniProt
Q14814
Accession Number mRNA
NM_005920
Chromosomal Location
1q22
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transcription Factors
Molecular Weight
55.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
MEF2D
Species
Human
Protein ID
NP_005911
Overview
Recombinant protein of human myocyte enhancer factor 2D (MEF2D)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/4209
Uniprot URL
https://www.uniprot.org/uniprot/Q14814
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_005920
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_005911
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