Galectin 3 (LGALS3) (NM_002306) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014]
Synonyms
CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2
Gene ID
3958
UniProt
P17931, A0A024R693
Accession Number mRNA
NM_002306
Chromosomal Location
14q22.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Secreted Protein
Molecular Weight
26 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
LGALS3
Species
Human
Protein ID
NP_002297
Overview
Recombinant protein of human lectin, galactoside-binding, soluble, 3 (LGALS3), transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3958
Uniprot URL
https://www.uniprot.org/uniprot/P17931
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_002306
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_002297
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items