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Galectin 3 (LGALS3) (NM_002306) Human Recombinant Protein

Product Specifications

Background

This gene encodes a member of the galectin family of carbohydrate binding proteins. Members of this protein family have an affinity for beta-galactosides. The encoded protein is characterized by an N-terminal proline-rich tandem repeat domain and a single C-terminal carbohydrate recognition domain. This protein can self-associate through the N-terminal domain allowing it to bind to multivalent saccharide ligands. This protein localizes to the extracellular matrix, the cytoplasm and the nucleus. This protein plays a role in numerous cellular functions including apoptosis, innate immunity, cell adhesion and T-cell regulation. The protein exhibits antimicrobial activity against bacteria and fungi. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Oct 2014]

Synonyms

CBP35; GAL3; GALBP; GALIG; L31; LGALS2; MAC2

Gene ID

3958

UniProt

P17931, A0A024R693

Accession Number mRNA

NM_002306

Chromosomal Location

14q22.3

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Secreted Protein

Molecular Weight

26 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

LGALS3

Species

Human

Protein ID

NP_002297

Overview

Recombinant protein of human lectin, galactoside-binding, soluble, 3 (LGALS3), transcript variant 1

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/3958

Uniprot URL

https://www.uniprot.org/uniprot/P17931

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_002306

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_002297

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