IL1RAP (NM_134470) Human Recombinant Protein

Product Specifications

Background

This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Jul 2018]

Overview

Recombinant protein of human interleukin 1 receptor accessory protein (IL1RAP), transcript variant 2

Synonyms

C3orf13; IL-1RAcP; IL1R3

Gene ID

3556

UniProt

Q9NPH3

Accession Number mRNA

NM_134470

Chromosomal Location

3q28

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Apoptosis, Cytokine-cytokine receptor interaction

Field of Research

Apoptosis, Cytokine-cytokine receptor interaction

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Secreted Protein, Transmembrane

Molecular Weight

40.8 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.