IL1RAP (NM_134470) Human Recombinant Protein
Product Specifications
Background
This gene encodes a component of the interleukin 1 receptor complex, which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in membrane-bound and soluble isoforms differing in their C-terminus. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq, Jul 2018]
Synonyms
C3orf13; IL-1RAcP; IL1R3
Gene ID
3556
UniProt
Q9NPH3
Accession Number mRNA
NM_134470
Chromosomal Location
3q28
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Apoptosis, Cytokine-cytokine receptor interaction
Field of Research
Apoptosis, Cytokine-cytokine receptor interaction
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Secreted Protein, Transmembrane
Molecular Weight
40.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
IL1RAP
Species
Human
Protein ID
NP_608273
Overview
Recombinant protein of human interleukin 1 receptor accessory protein (IL1RAP), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/3556
Uniprot URL
https://www.uniprot.org/uniprot/Q9NPH3
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_134470
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_608273
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