SRGAP1 (NM_020762) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a GTPase activator, working with the GTPase CDC42 to negatively regulate neuronal migration. The encoded protein interacts with the transmembrane receptor ROBO1 to inactivate CDC42. [provided by RefSeq, Sep 2016]
Synonyms
ARHGAP13; NMTC2
Gene ID
57522
UniProt
Q7Z6B7
Accession Number mRNA
NM_020762
Chromosomal Location
12q14.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Axon guidance
Field of Research
Axon guidance
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
124.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SRGAP1
Species
Human
Protein ID
NP_065813
Overview
Recombinant protein of human SLIT-ROBO Rho GTPase activating protein 1 (SRGAP1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/57522
Uniprot URL
https://www.uniprot.org/uniprot/Q7Z6B7
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_020762
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_065813
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