SRGAP1 (NM_020762) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a GTPase activator, working with the GTPase CDC42 to negatively regulate neuronal migration. The encoded protein interacts with the transmembrane receptor ROBO1 to inactivate CDC42. [provided by RefSeq, Sep 2016]

Overview

Recombinant protein of human SLIT-ROBO Rho GTPase activating protein 1 (SRGAP1)

Synonyms

ARHGAP13; NMTC2

Gene ID

57522

UniProt

Q7Z6B7

Accession Number mRNA

NM_020762

Chromosomal Location

12q14.2

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Axon guidance

Field of Research

Axon guidance

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Molecular Weight

124.1 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

SRGAP1

Species

Human

Protein ID

NP_065813

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/57522

Uniprot URL

https://www.uniprot.org/uniprot/Q7Z6B7

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_020762

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_065813

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