DCUN1D4 (NM_015115) Human Recombinant Protein
Product Specifications
Background
Contributes to the neddylation of all cullins by transfering NEDD8 from N-terminally acetylated NEDD8-conjugating E2s enzyme to different cullin C-terminal domain-RBX complexes which are necessary for the activation of cullin-RING E3 ubiquitin ligases (CRLs) .[UniProtKB/Swiss-Prot Function]
Synonyms
FLJ42355; KIAA0276
Gene ID
23142
UniProt
Q92564
Accession Number mRNA
NM_015115
Chromosomal Location
4q12
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Molecular Weight
29.8 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
DCUN1D4
Species
Human
Protein ID
NP_055930
Overview
Recombinant protein of human DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae) (DCUN1D4), transcript variant 2
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/23142
Uniprot URL
https://www.uniprot.org/uniprot/Q92564
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_015115
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_055930
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