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FXYD4 (NM_173160) Human Recombinant Protein

Selected Variant

PH37893M5

Size: 20 µg

Product Specifications

Background

This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD4, originally named CHIF for channel-inducing factor, has been shown to modulate the properties of the Na, K-ATPase, as has FXYD2, also known as the gamma subunit of the Na, K-ATPase, and FXYD7. Transmembrane topology has been established for FXYD4 and two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. Alternatively spliced transcript variants encoding the same protein have been found.[provided by RefSeq, May 2010]

Overview

Recombinant protein of human FXYD domain containing ion transport regulator 4 (FXYD4)

Synonyms

CHIF

Gene ID

53828

UniProt

P59646

Accession Number mRNA

NM_173160

Chromosomal Location

10q11.21

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Ion Channels: Other, Transmembrane

Molecular Weight

9.2 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

FXYD4

Species

Human

Protein ID

NP_775183

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/53828

Uniprot URL

https://www.uniprot.org/uniprot/P59646

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_173160

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_775183

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