FXYD4 (NM_173160) Human Recombinant Protein
Selected Variant
PH37893M5
Size: 20 µg
Product Specifications
Background
This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator. FXYD4, originally named CHIF for channel-inducing factor, has been shown to modulate the properties of the Na, K-ATPase, as has FXYD2, also known as the gamma subunit of the Na, K-ATPase, and FXYD7. Transmembrane topology has been established for FXYD4 and two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane. Alternatively spliced transcript variants encoding the same protein have been found.[provided by RefSeq, May 2010]
Overview
Recombinant protein of human FXYD domain containing ion transport regulator 4 (FXYD4)
Synonyms
CHIF
Gene ID
53828
UniProt
P59646
Accession Number mRNA
NM_173160
Chromosomal Location
10q11.21
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Ion Channels: Other, Transmembrane
Molecular Weight
9.2 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
FXYD4
Species
Human
Protein ID
NP_775183
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/53828
Uniprot URL
https://www.uniprot.org/uniprot/P59646
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_173160
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_775183
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