AGR3 (NM_176813) Human Recombinant Protein
Product Specifications
Background
This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This gene is expressed in ciliated airway epithelial cells and, in mouse, plays a role in ciliary beat frequency in multiciliated cells. This gene is also over-expressed in breast, ovarian, and prostrate cancers. [provided by RefSeq, Dec 2016]
Synonyms
AG-3; AG3; BCMP11; hAG-3; HAG3; PDIA18
Gene ID
155465
UniProt
Q8TD06
Accession Number mRNA
NM_176813
Chromosomal Location
7p21.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Secreted Protein
Molecular Weight
19 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
AGR3
Species
Human
Protein ID
NP_789783
Overview
Recombinant protein of human anterior gradient homolog 3 (Xenopus laevis) (AGR3)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/155465
Uniprot URL
https://www.uniprot.org/uniprot/Q8TD06
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_176813
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_789783
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