PLVAP (NM_031310) Human Recombinant Protein
Product Specifications
Background
Endothelial cell-specific membrane protein involved in the formation of the diaphragms that bridge endothelial fenestrae. It is also required for the formation of stomata of caveolae and transendothelial channels. Functions in microvascular permeability, endothelial fenestrae contributing to the passage of water and solutes and regulating transcellular versus paracellular flow in different organs. Plays a specific role in embryonic development.[UniProtKB/Swiss-Prot Function]
Synonyms
DIAR10; FELS; gp68; PV-1; PV1
Gene ID
83483
UniProt
Q9BX97
Accession Number mRNA
NM_031310
Chromosomal Location
19p13.11
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
50.4 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
PLVAP
Species
Human
Protein ID
NP_112600
Overview
Recombinant protein of human plasmalemma vesicle associated protein (PLVAP)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/83483
Uniprot URL
https://www.uniprot.org/uniprot/Q9BX97
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_031310
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_112600
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