SOX9 (NM_000346) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene recognizes the sequence CCTTGAG along with other members of the HMG-box class DNA-binding proteins. It acts during chondrocyte differentiation and, with steroidogenic factor 1, regulates transcription of the anti-Muellerian hormone (AMH) gene. Deficiencies lead to the skeletal malformation syndrome campomelic dysplasia, frequently with sex reversal. [provided by RefSeq, Jul 2008]
Synonyms
CMD1; CMPD1; SRA1; SRXX2; SRXY10
Gene ID
6662
UniProt
P48436
Accession Number mRNA
NM_000346
Chromosomal Location
17q24.3
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Activity
26040697
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Adult stem cells, Druggable Genome, Embryonic stem cells, ES Cell Differentiation/IPS, Induced pluripotent stem cells, Transcription Factors
Molecular Weight
56 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SOX9
Species
Human
Protein ID
NP_000337
Overview
Recombinant protein of human SRY (sex determining region Y) -box 9 (SOX9)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6662
Uniprot URL
https://www.uniprot.org/uniprot/P48436
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000346
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000337
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