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Estrogen Related Receptor alpha (ESRRA) (NM_004451) Human Recombinant Protein

Product Specifications

Background

The protein encoded by this gene is a nuclear receptor that is most closely related to the estrogen receptor. This protein acts as a site-specific transcription factor and interacts with members of the PGC-1 family of transcription cofactors to regulate the expression of most genes involved in cellular energy production as well as in the process of mitochondrial biogenesis. A processed pseudogene of ESRRA is located on chromosome 13q12.1. [provided by RefSeq, Jun 2019]

Synonyms

ERR1; ERRa; ERRalpha; ESRL1; NR3B1

Gene ID

2101

UniProt

P11474, Q569H8

Accession Number mRNA

NM_004451

Chromosomal Location

11q13.1

Expression System

HEK293T

Tag

C-Myc/DDK

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Druggable Genome, Nuclear Hormone Receptor, Transcription Factors

Molecular Weight

45.3 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.

Symbol

ESRRA

Species

Human

Protein ID

NP_004442

Overview

Purified recombinant protein of Homo sapiens estrogen-related receptor alpha (ESRRA)

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/2101

Uniprot URL

https://www.uniprot.org/uniprot/P11474

Accession Number mRNA URL

https://www.ncbi.nlm.nih.gov/nuccore/NM_004451

Protein ID Link

https://www.ncbi.nlm.nih.gov/nuccore/NP_004442

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