Estrogen Related Receptor alpha (ESRRA) (NM_004451) Human Recombinant Protein
Product Specifications
Background
The protein encoded by this gene is a nuclear receptor that is most closely related to the estrogen receptor. This protein acts as a site-specific transcription factor and interacts with members of the PGC-1 family of transcription cofactors to regulate the expression of most genes involved in cellular energy production as well as in the process of mitochondrial biogenesis. A processed pseudogene of ESRRA is located on chromosome 13q12.1. [provided by RefSeq, Jun 2019]
Overview
Purified recombinant protein of Homo sapiens estrogen-related receptor alpha (ESRRA)
Synonyms
ERR1; ERRa; ERRalpha; ESRL1; NR3B1
Gene ID
2101
UniProt
P11474, Q569H8
Accession Number mRNA
NM_004451
Chromosomal Location
11q13.1
Expression System
HEK293T
Tag
C-Myc/DDK
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
Molecular Weight
45.3 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
ESRRA
Species
Human
Protein ID
NP_004442
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2101
Uniprot URL
https://www.uniprot.org/uniprot/P11474
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004451
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004442
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