EXTL1 (NM_004455) Human Recombinant Protein
Product Specifications
Background
This gene is a member of the multiple exostoses (EXT) family of glycosyltransferases, which function in the chain polymerization of heparan sulfate and heparin. The encoded protein harbors alpha 1,4- N-acetylglucosaminyltransferase activity, and is involved in chain elongation of heparan sulfate and possibly heparin. [provided by RefSeq, Jul 2008]
Synonyms
EXTL
Gene ID
2134
UniProt
Q92935
Accession Number mRNA
NM_004455
Chromosomal Location
1p36.11
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Heparan sulfate biosynthesis, Metabolic pathways
Field of Research
Heparan sulfate biosynthesis, Metabolic pathways
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Transmembrane
Molecular Weight
74.5 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
EXTL1
Species
Human
Protein ID
NP_004446
Overview
Recombinant protein of human exostoses (multiple) -like 1 (EXTL1)
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/2134
Uniprot URL
https://www.uniprot.org/uniprot/Q92935
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_004455
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_004446
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