EXTL1 (NM_004455) Human Recombinant Protein

Product Specifications

Background

This gene is a member of the multiple exostoses (EXT) family of glycosyltransferases, which function in the chain polymerization of heparan sulfate and heparin. The encoded protein harbors alpha 1,4- N-acetylglucosaminyltransferase activity, and is involved in chain elongation of heparan sulfate and possibly heparin. [provided by RefSeq, Jul 2008]

Overview

Recombinant protein of human exostoses (multiple) -like 1 (EXTL1)

Synonyms

EXTL

Gene ID

2134

UniProt

Q92935

Accession Number mRNA

NM_004455

Chromosomal Location

1p36.11

Expression System

HEK293T

Tag

C-Myc/DDK

Related Pathways

Heparan sulfate biosynthesis, Metabolic pathways

Field of Research

Heparan sulfate biosynthesis, Metabolic pathways

Concentration

>50 ug/mL as determined by microplate BCA method

Purity

> 80% as determined by SDS-PAGE and Coomassie blue staining

Form

Liquid

Buffer

25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol

Function

Transmembrane

Molecular Weight

74.5 kDa

Storage Conditions

Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.