SUOX (NM_000456) Human Recombinant Protein
Product Specifications
Background
Sulfite oxidase is a homodimeric protein localized to the intermembrane space of mitochondria. Each subunit contains a heme domain and a molybdopterin-binding domain. The enzyme catalyzes the oxidation of sulfite to sulfate, the final reaction in the oxidative degradation of the sulfur amino acids cysteine and methionine. Sulfite oxidase deficiency results in neurological abnormalities which are often fatal at an early age. Alternative splicing results in multiple transcript variants encoding identical proteins. [provided by RefSeq, Jul 2008]
Synonyms
OTTHUMP00000158619; sulfite oxidase
Gene ID
6821
UniProt
P51687, A0A024RB79
Accession Number mRNA
NM_000456
Chromosomal Location
12q13.2
Expression System
HEK293T
Tag
C-Myc/DDK
Related Pathways
Sulfur metabolism
Field of Research
Sulfur metabolism
Concentration
>50 ug/mL as determined by microplate BCA method
Purity
> 80% as determined by SDS-PAGE and Coomassie blue staining
Form
Liquid
Buffer
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol
Function
Druggable Genome
Molecular Weight
60.1 kDa
Storage Conditions
Stable for 1 year at -20°C or below from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. For long-term storage, aliquot and store at -20°C or below. Avoid repeated freeze-thaw cycles.
Symbol
SUOX
Species
Human
Protein ID
NP_000447
Overview
Recombinant protein of human sulfite oxidase (SUOX), nuclear gene encoding mitochondrial protein, transcript variant 1
Gene ID URL
https://www.ncbi.nlm.nih.gov/gene/6821
Uniprot URL
https://www.uniprot.org/uniprot/P51687
Accession Number mRNA URL
https://www.ncbi.nlm.nih.gov/nuccore/NM_000456
Protein ID Link
https://www.ncbi.nlm.nih.gov/nuccore/NP_000447
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